Nube is a 25-year old man with two jobs. First off, he's a powerful exorcist who deals with the affairs between humans and yokai in his adopted home in Doumori. Second, and just as importantly, he's the teacher of class 5-3 of Doumori Elementary, both guiding and protecting them from the spiritual encounters they face. Both jobs are equal and important to him in their own ways: he chooses to protect the innocent and punish the wicked, both human and yokai, focusing primarily on those still young and innocent enough to have the need of a guardian. Source - Wikipedia
He is well versed in exorcism tools, but his main weapon is the "Oni no te", a real oni that was sealed in nube's left arm (in the anime, his arm is possesed; in the manga it's completely merged).