Ayra was born and raised in the eponymous capital of Isaac, a kingdom in the northeastern corner of the continent of Judgral, separated from its neighbors by desert. At the onset of Fire Emblem: Seisen no Keifu, her older brother Mariccle was king of Isaac. Mariccle was prepared for death when his sister Ayra went into exile with his son Shanan to the Kingdom of Verdane to escape the Isaacian-Grandbellian War and to preserve the main branch of the Odo bloodline in the occasion of his death. Upon arrival to Verdane, she and Shanan were taken hostage; being a swordwoman, Ayra had no choice but to work as a mercenary for Genoa castle to protect Shanan.