A loyal retainer of Nobunaga and the holder of Sakamoto Castle, Mitsuhide is thoughtful man with moderate political views and an open mind. He is a devoted husband and father to his wife, Hiroko, and their daughter, Tama. He suffers from failing eyesight. When Usagi makes medicine to improve his vision, Mitsuhide realizes that not all ninja are bad. He secretly helps the Iga ninja, though is eventually discovered by Ranmaru. Mitsuhide is forced to lead the eventual attack on Iga and Ranmaru's machinations force Mitsuhide out of Nobunaga's favour, Mitsuhide leads a rebellion against Nobunaga as revenge for Hiroko, who committed suicide in hopes it would atone for Mitsuhide's perceived slight on Nobunaga. Though Mitsuhide is believed to have died in the attack after being captured by Toyotomi Hideyoshi's forces, he continues to secretly live as a monk named Tenkai with Ieyasu.